Which hormone stimulates bicarbonate release from the pancreas?

Prepare for the Leaving Certificate Digestion Test with engaging questions and explanations. Ready yourself with multiple choice quizzes, hints, and deep insights. Be exam-ready now!

Multiple Choice

Which hormone stimulates bicarbonate release from the pancreas?

Explanation:
Secretin is the hormone that stimulates bicarbonate release from the pancreas. When acidic chyme enters the duodenum, S cells release secretin. This hormone travels to the pancreas and acts on the duct cells to boost secretion of bicarbonate-rich pancreatic juice, which neutralizes the acid and creates the right pH for digestive enzymes to work. Gastrin mainly enhances stomach acid production, not pancreatic bicarbonate. CCK prompts enzyme-rich pancreatic secretions and gallbladder contraction, but not bicarbonate release. Motilin regulates gut motility. So secretin is the best-fit hormone for driving bicarbonate release.

Secretin is the hormone that stimulates bicarbonate release from the pancreas. When acidic chyme enters the duodenum, S cells release secretin. This hormone travels to the pancreas and acts on the duct cells to boost secretion of bicarbonate-rich pancreatic juice, which neutralizes the acid and creates the right pH for digestive enzymes to work.

Gastrin mainly enhances stomach acid production, not pancreatic bicarbonate. CCK prompts enzyme-rich pancreatic secretions and gallbladder contraction, but not bicarbonate release. Motilin regulates gut motility. So secretin is the best-fit hormone for driving bicarbonate release.

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