Pepsinogen is produced by which cells of the stomach?

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Prepare for the Leaving Certificate Digestion Test with engaging questions and explanations. Ready yourself with multiple choice quizzes, hints, and deep insights. Be exam-ready now!

Multiple Choice

Pepsinogen is produced by which cells of the stomach?

Explanation:
Pepsinogen is the inactive precursor of the digestive enzyme pepsin, and it is produced by the chief cells of the stomach. These cells line the gastric glands in the fundus and body and are specialized to secrete enzyme precursors. When pepsinogen meets the stomach’s acidic environment, hydrochloric acid from neighboring parietal cells activates it to pepsin, which begins protein digestion. Parietal cells, in contrast, secrete acid and intrinsic factor; G cells release gastrin; ECL cells release histamine to boost acid secretion. So, the producer of pepsinogen is the chief cells.

Pepsinogen is the inactive precursor of the digestive enzyme pepsin, and it is produced by the chief cells of the stomach. These cells line the gastric glands in the fundus and body and are specialized to secrete enzyme precursors. When pepsinogen meets the stomach’s acidic environment, hydrochloric acid from neighboring parietal cells activates it to pepsin, which begins protein digestion. Parietal cells, in contrast, secrete acid and intrinsic factor; G cells release gastrin; ECL cells release histamine to boost acid secretion. So, the producer of pepsinogen is the chief cells.

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